Modified high performance concentric nebulizer for inductively coupled plasma optical emission spectrometry
Modified high performance concentric nebulizer for inductively coupled plasma optical emission spectrometry
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DOI：
10.1039/c2ja30118k
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发表时间：
2012-01-01
影响因子：
3.4
通讯作者：
Chiba, Koichi
中科院分区：
文献类型：
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作者：
Groombridge, Alexander S.;Inagaki, Kazumi;Chiba, Koichi
对高效三管同心雾化器（HPCN）进行了改进，并在0.25 ~ 0.8 mL min-1的液体流速下对样品引入电感耦合等离子体发射光谱（ICP-OES）进行了评价。通过更换雾化器的锥形中心毛细管（i.d./ o.d.：50 μ m/150 μ m），大口径管（内径/ o.d.：110 μ m/170 μ m）。通过将雾化器喷嘴的内径从250 μ m减小到200 μ m，雾化效率大大提高。在液体流速为0.8mL/min（-1）和雾化器气体流速为1 L/min（-1）时，由改性HPCN产生的初级气溶胶的Sauter平均直径（D-3，D-2）为3.4 μ m，并且超过90%（v/v）的气溶胶液滴的直径小于10 μ m。D-3、D-2值小于常规雾化器、C型Meinhard雾化器（8.2 μ m）、玻璃膨胀Conikal雾化器（15.8 μ m）、SeaSpray（14.8 μ m）和MiraMist（5.6 μ m）产生的值。通过无挡板旋风室产生的改性HPCN的三级气溶胶的量比具有相似尺寸分布的其他雾化器的量高约1.8至3.1倍。当液体流速相同时，使用改良HPCN的ICP-OES的灵敏度比使用其他雾化器的灵敏度高1.5至3.2倍。根据常用的Mg（II）/Mg（I）比值估计的血浆耐用性与传统雾化器相同或略好。HPCN也表现出良好的耐受性，高总溶解固体（TDS）使用20%的NaCl溶液。通过加标海水的回收试验和分析NMIJ CRM 7502-a白色米粉，对改良的HPCN进行验证。Na、Mg、P、K、Ca、Mn、Fe、Cu、Zn、Cd等10种元素的实测值与标准值吻合较好。我们的结论是，改进的HPCN是一个非常有用的雾化器，在大范围的样品流速的ICP-OES具有良好的性能。
The high performance triple-tube concentric nebulizer (HPCN) was modified and evaluated for sample introduction into inductively coupled plasma optical emission spectrometry (ICP-OES) at liquid flow rates of 0.25 to 0.8 mL min(-1). The acceptable liquid flow rate for the use of HPCN was extended by replacing the tapered center capillary tube of the nebulizer (i.d./o.d.: 50 mu m/150 mu m) with a large bore tube (i.d./o.d.: 110 mu m/170 mu m). The nebulization efficiency was much improved by reducing the inner diameter of the nebulizer nozzle from 250 mu m to 200 mu m. At a liquid flow rate of 0.8 mL min(-1) and a nebulizer gas flow rate of 1 L min(-1), the Sauter mean diameter (D-3,D-2) of the primary aerosol generated by the modified HPCN was 3.4 mu m, and over 90% (v/v) of the aerosol droplets were below 10 mu m in diameter. The D-3,D-2 value was smaller than those generated by conventional nebulizers, Meinhard nebulizer type C (8.2 mu m), Glass Expansion Conikal nebulizer (15.8 mu m), SeaSpray (14.8 mu m), and MiraMist (5.6 mu m). The amount of the tertiary aerosol of the modified HPCN generated through a non-baffled cyclone chamber was approximately 1.8 to 3.1 times higher than those of the other nebulizers, with similar size distributions. The sensitivity in ICP-OES with the modified HPCN was 1.5- to 3.2-fold higher than those with the other nebulizers when the liquid flow rates were the same. The plasma robustness estimated from the commonly used ratio Mg(II)/Mg(I) was the same or slightly better than that of the conventional nebulizers. The HPCN also showed a good tolerance to high total dissolved solids (TDS) using 20% NaCl solution. Validation of the modified HPCN was performed by a recovery test of spiked seawater and analyzing the NMIJ CRM 7502-a white rice flour. The observed values for the ten elements Na, Mg, P, K, Ca, Mn, Fe, Cu, Zn and Cd were in good agreement with their certified values. We concluded the modified HPCN is a very useful nebulizer for ICP-OES with good performance at a large range of sample flow rates.