Halogen-bonded cocrystals of donepezil with perfluorinated diiodobenzenes
Halogen-bonded cocrystals of donepezil with perfluorinated diiodobenzenes
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DOI：
10.1039/d0ce01065k
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发表时间：
2020-09
期刊：
影响因子：
3.1
通讯作者：
Vinko Nemec;Toni Vitasović;Dominik Cinčić
中科院分区：
文献类型：
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作者：
Vinko Nemec;Toni Vitasović;Dominik Cinčić
多奈哌齐是一种具有多个不同卤键受体位点的活性药物成分，已成功地与两种全氟卤键供体共结晶。所制备的共晶提供洞察有机分子的卤素键合潜力与增加的结构复杂性。
Donepezil, an active pharmaceutical ingredient with several different acceptor sites for halogen bonding has successfully been cocrystallized with two perfluorinated halogen bond donors. The prepared cocrystals provide insight into the halogen bonding potential of organic molecules with increased structural complexity.