Long-Term Outcomes of the Total or Supracervical Hysterectomy (TOSH) Trial.
Long-Term Outcomes of the Total or Supracervical Hysterectomy (TOSH) Trial.
复制标题
全子宫切除术或宫颈上子宫切除术 (TOSH) 试验的长期结果。
DOI：
10.1097/spv.0b013e3181cec343
复制
发表时间：
2010
影响因子：
1.6
通讯作者：
Learman,LeeA
中科院分区：
文献类型：
--
作者：
Greer,WJerod;Richter,HollyE;Wheeler,ThomasL;Varner,REdward;Szychowski,JeffM;Kuppermann,Miriam;Learman,LeeA
Objective:Participants in the multicenter, randomized Total or Supracervical Hysterectomy (TOSH) trial showed within-group improvement in pelvic floor symptoms 2 years postsurgery and no differences between supracervical (SCH) versus total hysterectomy (TAH). This study describes longer term outcomes from the largest recruiting site.Methods:Questionnaires addressing pelvic symptoms, sexual function, and health-related quality of life (HRQOL) were administered. Linear models and McNemar test were used.Results:Thirty-seven participants (69%) responded (19 TAH, 18 SCH); mean follow up was 9.1±0.7 years. No between-group differences emerged in urinary incontinence, voiding dysfunction, pelvic prolapse symptoms, and overall HRQOL. Within-group analysis showed significant improvement in the ability to have and enjoy sex (P= 0.002) and SF-36 physical component summary scores (P= 0.03) among women randomized to TAH.Conclusions:Nine years after surgery, TOSH participants maintained improvements in and show no major between-group differences in lower urinary tract or pelvic floor symptoms.
