VITAMIN-A AND RETINOIDS IN HEALTH AND DISEASE

VITAMIN-A AND RETINOIDS IN HEALTH AND DISEASE
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DOI:
10.1056/nejm198404193101605
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发表时间:
1984-01-01
影响因子:
158.5
通讯作者:
GOODMAN, DS
GOODMAN, DS
中科院分区:
医学1区
文献类型:
--
作者:
GOODMAN, DS

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在古埃及,夜盲症被认为是一种疾病。此外,从古代到20世纪初的文学作品中包含的评论似乎表明,人们认识到夜视所必需的一种饮食物质的存在。1913年,麦科勒姆和戴维斯报告说,某些食物中的一种必需的脂溶物质可以促进老鼠的生长。他们后来称这种物质为“脂溶A”,以区别于必需的水溶性营养素(“水溶性B”)。多位研究人员的进一步研究表明,“脂溶A”(后来命名为维生素A)不仅能维持生长,而且还能……
NIGHT blindness was recognized as a disease entity in ancient Egypt. Moreover, literature dating from ancient times to the early 20th century contains comments that appear to indicate recognition of the existence of a dietary substance necessary for night vision. In 1913 McCollum and Davis1reported that an essential lipid-soluble substance in certain foods promoted growth in rats. They later called this substance "Fat Soluble A," to distinguish it from essential water-soluble nutrients ("Water Soluble B"). Further studies by a number of investigators showed that "Fat Soluble A" (later named vitamin A) not only maintained growth but was capable of . . .