Increasing Latino adolescents' adherence to treatment for latent tuberculosis infection: A controlled trial
Increasing Latino adolescents' adherence to treatment for latent tuberculosis infection: A controlled trial
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DOI：
10.2105/ajph.93.11.1871
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发表时间：
2003-11-01
影响因子：
12.7
通讯作者：
Vera, AY
中科院分区：
文献类型：
--
作者：
Hovell, MF;Sipan, CL;Vera, AY
目标。我们试图确定指导患有潜伏性结核感染的拉丁裔青少年坚持异烟肼治疗的有效性。参与者（n = 286）被随机分配到依从性指导组、注意力控制组和常规护理组。依从性是通过访谈来衡量的，并通过尿液分析来验证。与关注组和常规护理组相比，指导组的依从性显著提高。双文化青少年比那些最不适应或最不适应文化的青少年更有可能坚持。年龄和危险行为。与坚持负相关。指导可以增加拉丁裔青少年对潜伏性结核病感染治疗的依从性，并应有助于对感染该疾病的高风险青少年进行结核病控制。
Objectives. We sought to determine the efficacy of coaching Latino adolescents with latent tuberculosis infection to adhere to isoniazid treatment.Methods.. Participants (n = 286) were randomly assigned to adherence coaching, attention control, or usual care groups. Adherence was measured via interviews and validated with urine assays.Results. Coaching resulted in significant increases in adherence compared with attention and usual care groups. Bicultural adolescents were more likely to be adherent than those most or least acculturated. Age and risk behavior were. negatively related to adherence.Conclusions. Coaching can increase Latino adolescents' adherence to treatment for latent tuberculosis infection and should contribute to tuberculosis control for adolescents at high risk of contracting the disease.