Epidemiology of Renal Cell Cancer
Epidemiology of Renal Cell Cancer
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DOI：
10.1016/j.hoc.2011.04.002
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发表时间：
2011-08-01
影响因子：
2.4
通讯作者：
Lindblad, Per
中科院分区：
文献类型：
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作者：
Cho, Eunyoung;Adami, Hans-Olov;Lindblad, Per
在许多国家，肾细胞癌（RCC）越来越多地在早期阶段被诊断出来，这可能是导致美国和许多欧洲国家近期肾细胞癌死亡率持平的原因。然而，在所有阶段，近50%的患者在诊断后5年内死亡。在高风险国家，吸烟和肥胖可能占所有意外病例的约40%。除了肥胖，高血压患病率的上升也可能起到越来越大的作用。其他一些职业和生活方式因素也可能影响肾癌的风险。遗传变异可能是人群发病率不同的一个重要因素。
Renal cell cancer (RCC) is increasingly diagnosed at an early stage in many countries, which likely contributes to the recent leveling of RCC mortality in the United States and many European countries. However, over all stages nearly 50% of the patients die within 5 years after diagnosis. Smoking and obesity may account for approximately 40% of all incidental cases in high-risk countries. Besides obesity, rising prevalence of hypertension may play a growing role. Several other occupational and lifestyle factors may also affect the risk of RCC. Genetic variations may be an important factor in the differing incidence among populations.