Real-time fMRI paradigm control, physiology, and behavior combined with near real-time statistical analysis

Real-time fMRI paradigm control, physiology, and behavior combined with near real-time statistical analysis
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DOI:
10.1006/nimg.1999.0457
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发表时间:
1999-08-01
期刊:
影响因子:
5.7
通讯作者:
Voyvodic, JT
Voyvodic, JT
中科院分区:
医学1区
文献类型:
--
作者:
Voyvodic, JT

文献摘要

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本研究提出了一种集成的方法,在线fMRI数据处理,结合实时范例控制和实时MR图像统计分析与近实时集成的fMRI行为和生理数据。实时范例涉及用于刺激呈现、生理监测、行为响应记录和扫描仪同步的多个独立处理流的精确定时控制。实时图像分析提供了高分辨率MR图像重建、头部运动检测、平移运动校正和t检验统计激活图,用于块设计或基于单次试验的范例。近实时分析允许在范例期间收集的生理和行为数据与MR时间序列相结合,并在扫描结束后的几分钟内提供扩展的数据过滤和统计处理。这种综合方法提高了fMRI在临床和研究中的可靠性。(C)北京:科学出版社.
This study presents an integrated approach to on-line fMRI data processing that combines real-time paradigm control and real-time MR image statistical analysis with nearly real-time integration of fMRI behavioral and physiological data. The real-time paradigms involve accurate timing control of multiple independent processing streams for stimulus presentation, physiological monitoring, behavioral response recording, and scanner synchronization. The real-time image analysis provides high resolution MR image reconstruction, head motion detection, translational motion correction, and t test statistical activation maps for either block design or single-trial based paradigms. The near real-time analysis allows physiological and behavioral data collected during a paradigm to be combined with the MR time series and provides extended data filtering and statistical processing within a few minutes after the end of the scan. This integrated approach improves fMRI reliability for both clinical and research studies. (C) 1999 Academic Press.