Increased joint loads during walking -: A consequence of pain relief in knee osteoarthritis
Increased joint loads during walking -: A consequence of pain relief in knee osteoarthritis
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DOI：
10.1016/j.knee.2006.08.005
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发表时间：
2006-12-01
期刊：
影响因子：
1.9
通讯作者：
Bliddal, Henning
中科院分区：
文献类型：
--
作者：
Henriksen, Marius;Simonsen, Erik B.;Bliddal, Henning
关节疼痛是膝骨关节炎（OA）的主要症状，但疼痛和疼痛缓解对膝关节步行力学的影响尚不清楚。在这项研究中，局部膝关节镇痛对膝关节骨关节炎患者在步行过程中的膝关节负荷的影响进行了研究。纳入一组健康受试者作为参考组。关节载荷根据标准化步行速度（4 km/h）获得的标准步态分析数据计算。在关节内注射10 mL利多卡因（I%）缓解疼痛之前和之后进行步态分析。注射前测量结果显示，与参照组相比，OA组的关节负荷较低。注射后，OA组行走时疼痛显著减轻，关节负荷在后期单次支撑阶段增加至与参考组相当的水平。尽管与参考组相比，患者行走时的膝关节压缩力较小，但疼痛缓解的效果可能会加速退行性变化。(c)2006 Elsevier B. V.保留所有权利。
Joint pain is a primary symptom in knee osteoarthritis (OA), but the effect of pain and pain relief on the knee joint mechanics of walking is not clear. In this study, the effects of local knee joint analgesia on knee joint loads during walking were studied in a group of knee osteoarthritis patients. A group of healthy subjects was included as a reference group. The joint loads were calculated from standard gait analysis data obtained with standardised walking speed (4 km/h). The gait analyses were performed before and after pain relief by intra-articular injections of 10 mL lidocaine (I%). Pre-injection measurements revealed lower joint loads in the OA group compared to the reference group. Following injections pain during walking decreased significantly and the joint loads increased in the OA group during the late single support phase to a level comparable to the reference group. Although the patients walked with less compressive knee joint forces compared to the reference group, the effects of pain relief may accelerate the degenerative changes. (c) 2006 Elsevier B.V. All rights reserved.