Axial Length Changes During Accommodation in Myopes and Emmetropes
Axial Length Changes During Accommodation in Myopes and Emmetropes
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DOI：
10.1097/opx.0b013e3181e87dd3
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发表时间：
2010-09-01
影响因子：
1.4
通讯作者：
Cheong, Shiow-Huoy
中科院分区：
文献类型：
--
作者：
Read, Scott A.;Collins, Michael J.;Cheong, Shiow-Huoy
目的.研究调节对年轻成人近视眼和正视眼人群眼轴长度（AXL）和一系列眼生物特征参数的影响。40名青年受试者在3种不同调节需求（0 D、3 D和6 D）下使用基于光学低相干反射原理的非接触式光学生物测量仪（Lenstar LS 900）进行眼生物测量。根据等效球镜屈光度将受试者分为正视眼（n = 19）和近视眼（n = 21）（平均正视眼屈光度-0.05 +/- 0.27 D，平均近视眼屈光度-1.82 +/- 0.84 D）。AXL随调节而显著改变，3D和6D调节刺激的平均增加分别为11.9 +/- 12.3 μ m和24.1 +/- 22.7 μ m。由于透镜厚度变化，即使在校正AXL数据的潜在误差后，与调节相关的显著轴向伸长仍然明显。对于3D和6D刺激，AXL的平均“校正”增加分别为5.2 +/- 11.2 μ m和7.4 +/- 18.9 μ m。无论数据是否校正，近视和正视人群在调节的AXL变化幅度方面没有显著差异。许多其他眼部生物特征参数，如前房深度、透镜厚度和玻璃体腔深度也随着调节而表现出显著变化。近视眼和正视眼人群在这些参数的变化幅度上也没有显着差异。眼睛经历与短暂的调节期相关的显著的轴向伸长，并且对于较大的调节需求，眼睛长度的这种变化的幅度增加，然而，近视和正视受试者的眼睛伸长的幅度没有显著差异。（Optom维斯科学2010; 87：656-662）
Purpose. To investigate the influence of accommodation on axial length (AXL) and a comprehensive range of ocular biometric parameters) in populations of young adult myopic and emmetropic subjects.Methods. Forty young adult subjects had ocular biometry measured using a noncontact optical biometer (Lenstar LS 900) based on the principle of optical low coherence reflectometry under 3 different accommodation demands (0 D, 3 D, and 6 D). Subjects were classified as emmetropes (n = 19) or myopes (n = 21) based on their spherical equivalent refraction (mean emmetropic refraction -0.05 +/- 0.27 D and mean myopic refraction -1.82 +/- 0.84 D).Results. AXL changed significantly with accommodation, with a mean increase of 11.9 +/- 12.3 mu m and 24.1 +/- 22.7 mu m for the 3 D and 6 D accommodation stimuli, respectively. A significant axial elongation associated with accommodation was still evident even after correction of the AXL data for potential error because of lens thickness change. The mean "corrected" increase in AXL was 5.2 +/- 11.2 mu m and 7.4 +/- 18.9 mu m for the 3 D and 6 D stimuli, respectively. There was no significant difference between the myopic and emmetropic populations in terms of the magnitude of change in AXL with accommodation, regardless of whether the data were corrected or not. A number of other ocular biometric parameters, such as anterior chamber depth, lens thickness, and vitreous chamber depth also exhibited significant change with accommodation. The myopic and emmetropic populations also exhibited no significant difference in the magnitude of change in these parameters with accommodation.Conclusions. The eye undergoes a significant axial elongation associated with a brief period of accommodation, and the magnitude of this change in eye length increases for larger accommodation demands, however, there is no significant difference in the magnitude of eye elongation in myopic and emmetropic subjects. (Optom Vis Sci 2010; 87:656-662)