Amide proton transfer imaging for differentiating benign ovarian cystic lesions: Potential of first time right
Amide proton transfer imaging for differentiating benign ovarian cystic lesions: Potential of first time right
复制标题
DOI：
10.1016/j.ejrad.2019.108656
复制
发表时间：
2019-11-01
影响因子：
3.3
通讯作者：
Honda, Hiroshi
中科院分区：
文献类型：
--
作者：
Ishimatsu, Keisuke;Nishie, Akihiro;Honda, Hiroshi
目的：探讨酰胺质子转移（APT）成像是否有助于鉴别良性卵巢囊性病变。材料和方法：本前瞻性研究共纳入19个病变18例良性卵巢囊性病变：浆液性囊腺瘤（SCA），n = 4;粘液性囊腺瘤（MCA），n = 9;或功能性囊肿（FC），n = 6。采用三种不同的预饱和脉冲持续时间：0.5、1.0和2.0 s进行APT成像。APT信号被定义为在3.5ppm处的磁化传递比不对称。在T1和T2加权像上计算的囊肿与肌肉的SI比值被定义为T1和T2比值。还生成表观扩散系数（ADC）图。结果：当使用2.0 s预饱和时，SCA、MCA和FC的APT信号分别为1.41 ± 0.71%、5.15 ± 1.92%和8.52 ± 1.17%。SCA和MCA之间存在显著差异（p
Purpose: To investigate whether amide proton transfer (APT) imaging is useful to differentiate benign ovarian cystic lesions.Materials and methods: This prospective study enrolled a total of 19 lesions in 18 patients with benign ovarian cystic lesion: serous cystadenoma (SCA), n = 4; mucinous cystadenoma (MCA), n = 9; or functional cyst (FC), n = 6. APT imaging was performed with three different presaturation pulse durations: 0.5, 1.0 and 2.0 s. APT signal was defined as magnetization transfer ratio asymmetry at 3.5 ppm. The SI ratios of cyst to muscle calculated on T1- and T2-weighted images were defined as T1- and T2-ratios. Apparent diffusion coefficient (ADC) maps were also generated. We compared the three cystic lesion groups' APT signals, T1-ratio, T2-ratio, and ADC.Results: When using 2.0 s of presaturation, the APT signals were 1.41 +/- 0.71% in SCA, 5.15 +/- 1.92% in MCA and 8.52 +/- 1.17% in FC. Significant differences were observed between SCA and MCA (p