The association between Trichomonas vaginalis infection and level of vaginal lactobacilli, in nonpregnant women

The association between Trichomonas vaginalis infection and level of vaginal lactobacilli, in nonpregnant women
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DOI:
10.1086/521307
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发表时间:
2007-10-01
影响因子:
6.4
通讯作者:
Sena, Arlene C.
Sena, Arlene C.
中科院分区:
医学2区
文献类型:
--
作者:
Torok, Michelle R.;Miller, William C.;Sena, Arlene C.

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阴道乳酸杆菌对滴虫病的影响尚不清楚。在3个治疗性传播疾病的诊所,我们招募了521名女性滴虫病患者和176名对照组。所有参与者都接受了体检和性传播感染检测,并完成了问卷调查。阴道乳酸杆菌水平低与滴虫病相关(比值比[ OR],2.2 [95%置信区间{CI},1.4-3.2])。调整协变量后,这种关联在教育水平较高的女性中仍然存在(OR,4.6 [95%CI,2.2-9.5]),但在教育水平较低的女性中则没有(OR,1.6 [95%CI,0.7-3.4])。阴道乳酸杆菌可能与受教育程度较高或相关行为因素的妇女的滴虫病有关。
The effect that vaginal lactobacilli have on trichomoniasis is not known. At 3 clinics for treatment of sexually transmitted disease, we recruited 521 female patients with trichomoniasis and 176 control subjects. All participants underwent physical examinations and testing for sexually transmitted infection and completed questionnaires. Low levels of vaginal lactobacilli were associated with trichomoniasis ( odds ratio [ OR], 2.2 [95% confidence interval {CI}, 1.4-3.2]). After adjustment for covariables, this association remained in women with a higher educational level ( OR, 4.6 [ 95% CI, 2.2-9.5]) but not in women with a lower educational level ( OR, 1.6 [ 95% CI, 0.7-3.4]). Vaginal lactobacilli may be associated with trichomoniasis in women with higher levels of education or a related behavioral factor.