Labyrinthine calcification in ears with otitis media and antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV): A report of two cases
Labyrinthine calcification in ears with otitis media and antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV): A report of two cases
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中耳炎合并抗中性粒细胞胞浆抗体相关性血管炎（OMAAV）耳迷路钙化二例报告
DOI：
10.1016/j.anl.2022.01.004
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发表时间：
2023
影响因子：
1.7
通讯作者：
Sone Michihiko
中科院分区：
文献类型：
--
作者：
Yoshida Tadao;Kobayashi Masumi;Sugimoto Satofumi;Naganawa Shinji;Sone Michihiko
抗神经细胞胞浆抗体相关性血管炎（OMAAV）中耳炎是一种新的中耳炎类型。OMAAV引起的听力损失可以通过早期检测和干预得到改善，但如果继续恶化并导致耳聋，则恢复患者的听力具有挑战性。当双侧耳聋发生时，人工耳蜗植入手术是改善听力的唯一途径。例1显示单侧耳蜗钙化，例2显示双侧耳蜗钙化。在病例1中，在没有钙化的耳朵上进行了CI手术，在病例2中，在具有轻度钙化的耳朵上进行了CI手术。病例2从鼓腔到乳突存在肉芽，圆窗关闭，耳蜗基回变窄。OMAAV引起的耳蜗钙化至今未见报道。在早期阶段通过计算机断层扫描检测这些变化并在适当的时间进行CI手术是至关重要的，因为在因OMAAV而耳聋的患者中，听力改善是不期望的。
Otitis media with antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV) has been proposed as a new type of otitis media. The hearing loss caused by OMAAV can be expected to improve with early detection and intervention, but if it continues to worsen and leads to deafness, it is challenging to recover the patient's hearing. When bilateral deafness occurs, cochlear implant (CI) surgery is the only way to improve hearing. Here, Case 1 showed unilateral cochlear calcification, and Case 2 showed bilateral cochlear calcification. In Case 1, CI surgery was performed on the ear lacking calcification, and in Case 2 it was performed on the ear with milder calcification. In Case 2, granulation was present from the tympanic space to the mastoid, the round window was closed, and the basal turn of the cochlea was narrowed. Such calcification of the cochlea caused by OMAAV has not been reported so far. It is essential to detect these changes by computed tomography scans at an early stage and to perform CI surgery at an appropriate time, because hearing improvements are not expected in patients who become deaf because of OMAAV.