Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children
Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children
复制标题
正常儿童和易患中耳炎儿童生命前三年的鼻咽菌群
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
P. Ogra
中科院分区：
文献类型：
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作者：
H. Faden;L. Brodsky;Mary Jane Waz;J. Stanievich;J. Bernstein;P. Ogra
对 110 名儿童进行了前瞻性评估，对生命前 3 年进行了随访，评估了三种主要中耳病原体（肺炎链球菌、不可分型流感嗜血杆菌和卡他莫拉菌）的鼻咽携带情况。研究结果表明，在一般幼儿群体中，患有呼吸道疾病时，鼻咽部中耳病原体的携带量显着增加；然而，易患中耳炎的儿童即使在健康期间也表现出以异常高的比率携带不可分型流感嗜血杆菌的倾向。这种携带不可分型流感嗜血杆菌的倾向可能解释了为什么不可分型流感嗜血杆菌是复发性或慢性中耳炎的主要原因。
Nasopharyngeal carriage of the three major middle ear pathogens (Streptococcus pneumoniae, nontypeable Hemophilus influenzae, and Moraxella catarrhalis) was evaluated prospectively in a group of 110 children followed up for the first 3 years of life. The findings suggested that nasopharyngeal carriage of middle ear pathogens increases significantly during respiratory illness among the general population of young children; however, otitis-prone children demonstrated a tendency to carry nontypeable H influenzae at an unusually high rate even during health. This propensity to carry nontypeable H influenzae might explain why nontypeable H influenzae is a major cause of recurrent or chronic otitis media.
DOI：
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发表时间：
1990
期刊：
The Pediatric infectious disease journal
影响因子：
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作者：
Faden,H;Stanievich,J;Brodsky,L;Bernstein,J;Ogra,PL
通讯作者：
Ogra,PL