Surgical Site Infection by Methicillin Resistant Staphylococcus aureus- on Decline?

Surgical Site Infection by Methicillin Resistant Staphylococcus aureus- on Decline?
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DOI:
10.7860/jcdr/2016/21664.8587
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发表时间:
2016-09-01
影响因子:
0.2
通讯作者:
Konar, Jayashree
Konar, Jayashree
中科院分区:
其他
文献类型:
--
作者:
Bhattacharya, Susmita;Pal, Kuhu;Konar, Jayashree

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简介:手术部位感染(SSI)是最常见的医疗保健相关感染,可以通过抗生素预防可能的致病微生物来避免。金黄色葡萄球菌(Staphylococcus aureus,MRSA)在SSI的病因学中起着重要作用,而耐甲氧西林金黄色葡萄球菌(Methicillin Resistant Staphylococcus aureus,MRSA)在处理术后伤口感染时恰好是一个问题。2009年7月至2012年12月在西孟加拉加尔各答的Nil Ratan Sircar医学院进行了一项横断面研究。共进行了19,359例外科手术,其中记录了3003例培养阳性SSI。临床样本采集自不同专业的疑似SSI患者,包括男性和女性。根据CLSI,2007指南处理样本。用头孢西丁纸片法(抑菌圈为1.00 μ g/ml)对分离的金黄色葡萄球菌进行耐药性检测,
Introduction: Surgical Site Infection (SSI) is the most common healthcare associated infection that could be averted by antibiotics prophylaxis against the probable offending organisms. As Staphylococcus aureus has been playing a substantial role in the aetiology of SSIs, Methicillin Resistant Staphylococcus aureus (MRSA) happens to be a problem while dealing with the postoperative wound infection.Aim: To determine the prevalence of SSI caused by MRSA and the antibiotic sensitivity pattern of MRSA.Materials and Methods: A cross-sectional study was conducted at Nil Ratan Sircar Medical College, Kolkata, West Bengal from July 2009 to December 2012. A total of 19,359 surgical procedures were done of which 3003 culture positive SSIs have been documented. The clinical samples were collected from patients of both sexes and all ages suspected to be suffering from SSI from different specialities. Samples were processed according to CLSI, 2007 guidelines. The isolated strains of Staphylococcus aureus were screened for MRSA by detection of resistance to Cefoxitin disc (zone of inhibition was