CHARACTERIZATION OF THE EXPRESSED GENE AND SEVERAL PROCESSED PSEUDOGENES FOR THE MOUSE RIBOSOMAL-PROTEIN L30 GENE FAMILY
CHARACTERIZATION OF THE EXPRESSED GENE AND SEVERAL PROCESSED PSEUDOGENES FOR THE MOUSE RIBOSOMAL-PROTEIN L30 GENE FAMILY
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DOI：
10.1128/mcb.4.11.2518
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发表时间：
1984-01-01
影响因子：
5.3
通讯作者：
PERRY, RP
中科院分区：
文献类型：
--
作者：
WIEDEMANN, LM;PERRY, RP
Five cloned genes encoding the mouse ribosomal protein L30 were isolated from a recombinant DNA library and characterized by restriction mapping and nucleotide sequence analysis. Only 1 of these genes has introns and is expressed; the others are inactive processed pseudogenes. The expressed gene consists of 5 exons and 4 introns spanning 2723 nucleotides. Transcripts of this gene are processed into the mature L30 mRNA by pathways that exhibit both constraints and flexibility with regard to the order of intron excision. The L30 mRNA which is 457-468 nucleotides in length excluding the polyadenylic acid tail, exhibits some microheterogeneity at its 3'' end and encodes basic protein of 115 amino acids. The 5'' portion of the rpL30 gene has some novel features which are remarkably similar to the previously characterized mouse rpL32 gene. These include homologous sequences in the -60 to -340 region, the absence of a good TATA consensus sequence and the presence of a palindromic pyrimidine sequence that spans the cap site.
