[Sentinel node navigation surgery].
[Sentinel node navigation surgery].
复制标题
[前哨淋巴结导航手术]。
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
Y. Kitagawa
中科院分区：
文献类型：
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作者：
H. Takeuchi;Y. Kitagawa
前哨淋巴结（Sentinel nodes，SN）被定义为原发肿瘤部位的第一个引流淋巴结，并且它们被认为是沿着原发病灶的淋巴引流路线的第一个可能的微转移部位。最近的荟萃分析和一项关于早期胃癌SN标测的前瞻性多中心试验显示，SN检出率和淋巴结状态确定的准确性可接受。采用放射性胶体和蓝色染料的双示踪方法目前被认为是稳定检测早期胃癌SN的最可靠方法。然而，新技术如吲哚菁、绿色、红外或荧光成像可能会使胃癌的SN标测程序发生革命性变化。对于早期胃癌，建立基于SN理念的个体化、微创化治疗方案，可保留患者的生活质量。内镜下黏膜下剥离术或非暴露内镜下翻壁术联合SN标测和淋巴盆剥离术有望成为治愈cN 0早期胃癌患者的一种有前景的、理想的微创、功能保留治疗方法。
Sentinel nodes (SNs) are defined as the first draining lymph nodes from the primary tumor site, and they are thought to be the first possible site of micrometastasis along the route of lymphatic drainage from the primary lesion. Recent meta-analyses and a prospective multicenter trial of SN mapping for early gastric cancer have shown acceptable SN detection rates and accuracy of determination of lymph node status. A dual-tracer method that employs radioactive colloids and blue dyes is currently considered the most reliable method for the stable detection of SNs for early-stage gastric cancer. However the new technologies such as indocyanine green infrared or fluorescence imaging may revolutionize the SN mapping procedures in gastric cancer. For early gastric cancer, the establishment of individualized, minimally invasive treatments based on SN concept can retain the patients’ quality of life. The combination of endoscopic submucosal dissection or non-exposed endoscopic wall-inversion surgery with SN mapping and lymphatic basin dissection is expected to become a promising, ideal minimally invasive, function-preserving treatment to cure patients with cN0 early gastric cancer.
影响因子：
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作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
通讯作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
影响因子：
45.3
作者：
Bilchik, AJ;Saha, S;Hoon, DSB
通讯作者：
Hoon, DSB