Inactivation of ompR promotes precocious swarming and flhDC expression in Xenorhabdus nematophila
Inactivation of ompR promotes precocious swarming and flhDC expression in Xenorhabdus nematophila
复制标题
DOI：
10.1128/jb.185.17.5290-5294.2003
复制
发表时间：
2003-09-01
影响因子：
3.2
通讯作者：
Forst, S
中科院分区：
文献类型：
--
作者：
Kim, DJ;Boylan, B;Forst, S
响应调节器OmpR参与对环境挑战的许多适应性响应。本研究探讨了OmpR在共生致病菌嗜黄杆菌的群集行为和群集细胞分化中的作用。群集开始4小时前ompR突变株比野生型细胞。性早熟群集与fliC表达升高、早期鞭毛形成和细胞伸长相关。相对于野生型中的水平，在ompR菌株中在群集的早期期间flhDC mRNA的水平升高。这些发现表明OmpR参与flhDC表达和鞭毛产生的时间调节，并证明这种反应调节剂在X的群集行为中起作用。喜食草
The response regulator OmpR is involved in numerous adaptive responses to environmental challenges. The role that OmpR plays in swarming behavior and swarm-cell differentiation in the symbiotic-pathogenic bacterium Xenorhabdus nematophila was examined in this study. Swarming began 4 h sooner in an ompR mutant strain than in wild-type cells. Precocious swarming was correlated with elevated expression of fliC, early flagellation, and cell elongation. The level of flhDC mRNA was elevated during the early period of swarming in the ompR strain relative to the level in the wild type. These findings show that OmpR is involved in the temporal regulation of flhDC expression and flagellum production and demonstrate that this response regulator plays a role in the swarming behavior of X. nematophila.