1994-2004: 10 years of research on the anaerobic oxidation of ammonium
1994-2004: 10 years of research on the anaerobic oxidation of ammonium
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DOI：
10.1042/bst0330119
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发表时间：
2005-02-01
影响因子：
3.9
通讯作者：
Strous, M
中科院分区：
文献类型：
--
作者：
Jetten, MSM;Cirpus, I;Strous, M
以亚硝酸盐为主要电子受体的专性厌氧氨氧化(ANAMMOX)反应是由类假单胞菌Brocadio anammoxidans、Kuenenia stuttgortiens和Scaldua sorokinii催化的。厌氧氨氧化细菌使用以肼为中间体的复杂反应机制。它们有一个独特的原核细胞器，anammoxosome，被梯状脂类包围，它唯一的含有联氨氧化还原酶作为主要蛋白质，以一对一的方式结合亚硝酸盐和氨。除了特殊的微生物外，Anammox在海洋氮循环中也非常重要，并被证明是处理高浓度含氮废水的一种非常好的替代方案。随着Stuttgartisis基因组在法国埃弗里Gencope的组装，Anammox反应进入了基因组和蛋白质组时代，使这一迷人的微生物过程的许多有趣方面得以阐明。
The obligately anaerobic ammonium oxidation (anammox) reaction with nitrite as primary electron acceptor is catalysed by the planctomycete-like bacteria Brocadio anammoxidans, Kuenenia stuttgortiensis and Scalindua sorokinii. The anammox bacteria use a complex reaction mechanism involving hydrazine as an intermediate. They have a unique prokaryotic organelle, the anammoxosome, surrounded by ladderane lipids, which exclusively contains the hydrazine oxidoreductase as the major protein to combine nitrite and ammonia in a one-to-one fashion. in addition to the peculiar microbiology, anammox was shown to be very important in the oceanic nitrogen cycle, and proved to be a very good alternative for treatment of high-strength nitrogenous waste streams. With the assembly of the K. stuttgartiensis genome at Genoscope, Evry, France, the anammox reaction has entered the genomic and proteomic era, enabling the elucidation of many intriguing aspects of this fascinating microbial process.