Racial and ethnic disparities in assisted reproductive technology outcomes in the United States.

Racial and ethnic disparities in assisted reproductive technology outcomes in the United States.
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DOI:
10.1016/j.fertnstert.2008.10.061
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发表时间:
2010-02
影响因子:
6.7
通讯作者:
Society for Assisted Reproductive Technology Writing Group
Society for Assisted Reproductive Technology Writing Group
中科院分区:
医学2区
文献类型:
--
作者:
Fujimoto VY;Luke B;Brown MB;Jain T;Armstrong A;Grainger DA;Hornstein MD;Society for Assisted Reproductive Technology Writing Group

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评估美国辅助生殖技术(ART)结局的种族差异。历史队列研究。临床数据。2004-2006年辅助生殖技术临床结果报告系统在线数据库中共有139 027个ART周期,仅限于白色、亚洲、黑人和西班牙裔妇女。没有。Logistic回归分析用于建立妊娠和活产的几率模型;在单胎和双胎中,早产和胎儿生长受限的几率。结果以校正比值比表示,以白色女性作为参照组。亚洲人的怀孕几率降低(0.86),所有群体的活产几率都降低:亚洲人(0.90),黑人(0.62)和西班牙裔(0.87)女性。在单胎婴儿中,所有三个少数民族组的所有婴儿的中度和重度生长受限均增加(亚洲人[1.78,2.05];黑人[1.81,2.17];西班牙裔[1.36,1.64]),黑人(1.79)和西班牙裔妇女(1.22)的早产增加。在双胞胎中,亚洲(1.30)和黑人妇女(1.97)的婴儿中度生长受限的几率增加,黑人妇女(3.21)的婴儿重度生长受限的几率增加。黑人早产的几率增加(1.64),亚洲人早产的几率减少(0.70)。抗逆转录病毒治疗的结果因种族而异。
To evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States. Historical cohort study. Clinic-based data. A total of 139,027 ART cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System online database for 2004–2006, limited to white, Asian, black, and Hispanic women. None. Logistic regression was used to model the odds of pregnancy and live birth; among singletons and twins, the odds of preterm birth and fetal growth restriction. Results are presented as adjusted odds ratios, with white women as the reference group. The odds of pregnancy were reduced for Asians (0.86), and the odds of live birth were reduced for all groups: Asian (0.90), black (0.62), and Hispanic (0.87) women. Among singletons, moderate and severe growth restriction were increased for all infants in all three minority groups (Asians [1.78, 2.05]; blacks [1.81, 2.17]; Hispanics [1.36, 1.64]), and preterm birth was increased among black (1.79) and Hispanic women (1.22). Among twins, the odds for moderate growth restriction were increased for infants of Asian (1.30) and black women (1.97), and severe growth restriction was increased among black women (3.21). The odds of preterm birth were increased for blacks (1.64) and decreased for Asians (0.70). There are significant disparities in ART outcomes according to ethnicity.