SCORPION, a molecular database of scorpion toxins

SCORPION, a molecular database of scorpion toxins
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DOI:
10.1016/s0041-0101(01)00182-9
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发表时间:
2002-01-01
期刊:
影响因子:
2.8
通讯作者:
Brusic, V
Brusic, V
中科院分区:
医学4区
文献类型:
--
作者:
Srinivasan, KN;Gopalakrishnakone, P;Brusic, V

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人们对毒素研究的兴趣日益浓厚,以及对更好的结构和功能注释的需求,产生了改进毒素领域数据管理的需求。分子数据库 SCORPION 包含 200 多条完整引用的蝎毒素数据,包括蝎毒素的一级序列、三维结构、结构和功能注释以及相关文献参考。 SCORPION 有一组搜索工具,允许用户提取数据并执行特定查询。这些条目是根据公共数据库和文献汇编而成的,清除了错误,并补充了额外的结构和功能信息。蝎毒素的分类为扩展和澄清现有的结构和功能分类提供了基础。 SCORPION 中的生物信息学模块有助于对蝎子毒素进行分类分析,并识别与蝎子毒素特定结构或功能特性相关的序列模式。 SCORPION 数据库可通过互联网访问:sdme.krdl.org.sg:8080/scorpion。 (C) 2001 Elsevier Science Ltd. 保留所有权利。
Increasing interest in the studies of toxins and the requirements for better structural and functional annotations have created a need for improved data management in the field of toxins. The molecular database, SCORPION, contains more than 200 entries of fully referenced scorpion toxin data including primary sequences, three-dimensional structures, structural and functional annotations of scorpion toxins along with relevant literature references. SCORPION has a set of search tools that allow users to extract data and perform specific queries. These entries have been compiled from public databases and literature, cleaned of errors and enriched with additional structural and functional information. The grouping of scorpion toxins provides a basis for extending and clarifying the existing structural and functional classifications. The bioinformatics modules in SCORPION facilitate analyses aimed at classification of scorpion toxins and identification of sequence patterns associated with specific structural or functional properties of scorpion toxins. The SCORPION database is accessible via the Internet at sdme.krdl.org.sg:8080/scorpion. (C) 2001 Elsevier Science Ltd. All rights reserved.