Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance.
Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance.
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DOI：
10.4178/epih/e2015020
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发表时间：
2015
影响因子：
3.8
通讯作者：
Kandi S
中科院分区：
文献类型：
--
作者：
Kandi V;Kandi S
多种微生物病原体之间的多重耐药性的出现已经引起医学界的严重关注，限制了抗生素的选择。考虑到可能需要几十年才能合成对抗耐药病原体的新的抗微生物药物，已经开始寻找传统抗微生物剂的替代品。在他的论文中，我们试图回顾纳米颗粒的物理化学性质，它们的作用方式以及在医学和研究中的潜在用途，特别是抗菌性能。近年来，纳米分子和纳米颗粒已被广泛研究，因为它们不仅可用作抗生素，还可用作运载抗生素或其他药剂（如癌症化疗剂）至靶位点并限制对宿主细胞的损伤的载体。纳米分子的抗微生物活性得到了积极评价。纳米粒子的抗生物膜活性，纳米材料作为药物载体的应用，表明了它们在医学和研究中的重要性。
The emergence of multi-drug resistance among various microbial pathogens has been a cause of serious concern to the medical world, limiting the choice of antibiotics. Considering that it may take decades to synthesize new antimicrobial drugs that combat resistant pathogens, the search for alternatives to conventional antimicrobial agents has begun. In his paper we attempted to review the physico-chemical properties of nanoparticles, their modes of action and potential use in medicine and research with special reference to antimicrobial properties. Nanomolecules and nanoparticles have in recent years been extensively studied for their utility not only as antibiotics but also as vehicles to carry antibiotics or other agents such as cancer chemotherapeutics to target sites and limit damage to host cells. Nanomolecules were positively evaluated for their antimicrobial activities. Anti-biofilm activities of nanoparticles, utility of nanomaterials as carrier agents of drugs signifies their importance in medicine and research.