Three-Dimensional Tomographic Features of Dome-Shaped Macula by Swept-Source Optical Coherence Tomography
Three-Dimensional Tomographic Features of Dome-Shaped Macula by Swept-Source Optical Coherence Tomography
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DOI：
10.1016/j.ajo.2012.08.007
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发表时间：
2013-02-01
影响因子：
4.2
通讯作者：
Yoshimura, Nagahisa
中科院分区：
文献类型：
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作者：
Ellabban, Abdallah A.;Tsujikawa, Akitaka;Yoshimura, Nagahisa
目的：采用扫频光学相干断层扫描 (OCT) 研究圆顶形黄斑的断层扫描和病理形态学特征。设计：前瞻性横断面研究。方法：采用 1050 nm 扫频 OCT 对 51 只患有圆顶形黄斑的高度近视眼（35 名患者）的黄斑区域进行研究。通过覆盖 12 x 8-mm(2) 区域的光栅扫描获得三维 (3-D) 数据集；通过视网膜色素上皮 (RPE) 的自动分割构建后极部的 3D 图像。结果：在所有重建的 RPE 3D 图像中，后葡萄肿内可见 2 个向外的凹陷，并且在这 2 个凹陷之间形成水平脊。其中 42 只眼睛的水平脊呈带状。穿过中央凹的垂直 OCT 截面显示 RPE 的凸形结构，但水平截面显示几乎平坦的 RPE 线。 9 只眼睛的 3D 图像显示葡萄肿内有典型的圆顶形凸面。 OCT 扫描显示巩膜外表面没有向外突出，但巩膜明显变薄，与 RPE 的 2 个向外凹陷一致。中央凹的巩膜 (518.6 +/- 97.6 μm) 明显厚于中央凹旁区域所有 4 个象限的巩膜（范围，277.2 至 360.3 μm；P < .001）。结论：在具有圆顶形黄斑的高度近视眼中，由于巩膜后葡萄肿的不均匀变薄，在后葡萄肿内形成了水平脊。巩膜。 （美国眼科杂志 2013 年；155:320-328。(c) 2013 年，Elsevier Inc. 保留所有权利。）
PURPOSE: To study the tomographic and pathomorphologic features of dome-shaped maculas with swept-source optical coherence tomography (OCT).DESIGN: Prospective, cross-sectional study.METHODS: The macular area of 51 highly myopic eyes (35 patients) with dome-shaped maculas was studied with swept-source OCT at 1050 nm. Three-dimensional (3-D) data sets were obtained with raster scanning covering a 12 x 8-mm(2) area; 3-D images of the posterior pole were constructed by autosegmentation of the retinal pigment epithelium (RPE).RESULTS: In all reconstructed 3-D images of the RPE, 2 outward concavities were seen within the posterior staphyloma and a horizontal ridge was formed between these 2 concavities. In 42 of these eyes, this horizontal ridge was band shaped. The vertical OCT section through the fovea showed a convex configuration of RPE, but the horizontal section showed an almost flat RPE line. In 9 eyes, 3-D images showed a typical dome-shaped convexity within the staphyloma. OCT scans showed no outward protrusions in the external scleral surface, but marked scleral thinning was seen consistent with the 2 outward concavities of the RPE. The sclera of the fovea (518.6 +/- 97.6 mu m) was significantly thicker than that in all 4 quadrants of the parafoveal area (range, 277.2 to 360.3 mu m; P < .001).CONCLUSIONS: In highly myopic eyes with a domeshaped macula, a horizontal ridge is formed within the posterior staphyloma by uneven thinning of the sclera. (Am J Ophthalmol 2013;155:320-328. (c) 2013 by Elsevier Inc. All rights reserved.)