Acute generalized exanthematous pustulosis following a spider bite: Report of 3 cases

Acute generalized exanthematous pustulosis following a spider bite: Report of 3 cases
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DOI:
10.1016/j.jaad.2006.05.010
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发表时间:
2006-09-01
影响因子:
13.8
通讯作者:
Halevy, Sima
Halevy, Sima
中科院分区:
医学1区
文献类型:
--
作者:
Batya, B. Davidovici;Dyachenko, Pavel;Halevy, Sima

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摘要急性泛发性暴露性脓疱病是一种罕见的严重皮肤不良反应,主要由药物引起。作为两项前瞻性多国研究的一部分,我们招募了22例AGEP病例中的3例(13.6%),发生在蜘蛛咬伤后24至48小时。我们认为蜘蛛咬伤可能是AGEP的触发因素。
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction caused mostly by drugs. Three of 22 AGEP cases (13.6%), recruited by us as part of two prospective multinational studies, occurred 24 to 48 hours after a spider bite. We suggest that a spider bite is a possible trigger for AGEP.