Neuron loss in the nucleus basalis of meynert in parkinsonism‐dementia complex of Guam
Neuron loss in the nucleus basalis of meynert in parkinsonism‐dementia complex of Guam
复制标题
关岛帕金森病-痴呆症患者 meynert 基底核神经元丢失
作者：
I. Nakano;A. Hirano
在两例帕金森病痴呆复合体的关岛(PDG)患者中，观察了向大脑新皮质供应弥漫性胆碱能纤维的Meynert基底核。与年龄匹配的非关岛对照组相比，两例PDG患者的基底核表现出广泛的神经元丢失，提示有必要研究PDG患者脑内胆碱能酶的活性。
The nucleus basalis of Meynert, which supplies diffuse cholinergic fibers to the cerebral neocortex, was investigated in two cases of parkinsonism‐dementia complex of Guam (PDG). The nucleus basalis of the two PDG patients showed extensive neuron loss when compared with age‐matched non‐Guamanian controls, suggesting the necessity of investigating activity of cholinergic enzymes in the brains of patients with PDG.