Serological Study of Bartonella henselae in Cat Scratch Disease in Japan

Serological Study of Bartonella henselae in Cat Scratch Disease in Japan
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日本猫抓病汉赛巴尔通体的血清学研究

DOI:
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发表时间:
1996
影响因子:
2.6
通讯作者:
Kyuichi Tanikawa
Kyuichi Tanikawa
中科院分区:
医学4区
文献类型:
--
作者:
H. Yoshida;N. Kusaba;Kei Omachi;Norihisa Miyazaki;M. Yamawaki;Yuichiroh Tsuji;Keita Nakahara;M. Sumino;Masanori Noudomi;Yutaka Shimokawa;Kyuichi Tanikawa

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很明显,汉赛巴尔通体是猫抓病(CSD)的常见原因。间接荧光抗体(IFA)试验用于检测B的IgG和IgM抗体。10例CSD患者中5例(50%)血清IgG抗体滴度为1:128或更高,2例(20%)血清IgM抗体滴度为1:20或更高。7名无症状患者家属中有1人(14%)有抗B IgG抗体。henselae,滴度为1:256。抗B IgM抗体。在患者家属血清中未检出汉赛原虫。抗B的IgG和IgM抗体。在健康对照组的血清中未检测到汉赛氏菌。这些数据表明,B。henselae可能是日本CSD的一个原因。
It has become clear that Bartonella henselae is a common cause of cat scratch disease (CSD). The indirect fluorescence antibody (IFA) test for detection of IgG and IgM antibodies to B. henselae concerning CSD showed that 5 (50%) of 10 patients with CSD had a serum IgG antibody titer of 1:128 or more and that 2 (20%) patients had a serum IgM antibody titer of 1:20 or more. One of 7 asymptomatic members of patients' families (14%) had IgG antibody to B. henselae at a titer of 1:256. IgM antibody to B. henselae was not detected in sera from the patients' families. Both IgG and IgM antibodies to B. henselae were not detected in sera from the healthy control group. These data suggest that B. henselae may be a cause of CSD in Japan.