Repetitive Head Impacts and Chronic Traumatic Encephalopathy
Repetitive Head Impacts and Chronic Traumatic Encephalopathy
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DOI：
10.1016/j.nec.2016.05.009
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发表时间：
2016-10-01
影响因子：
2.6
通讯作者：
Huber, Bertrand R.
中科院分区：
文献类型：
--
作者：
McKee, Ann C.;Alosco, Michael L.;Huber, Bertrand R.
慢性创伤性脑病（CTE）是一种独特的神经退行性疾病，由于反复头部撞击而发生。CTE只能通过死后脑组织的神经病理学检查来诊断。CTE是一种独特的疾病，其特征性病变可以可靠地与其他神经退行性疾病区分开来。CTE与暴力行为、爆炸性、失控、抑郁、自杀、记忆丧失和认知变化有关。越来越多的证据表明，CTE影响业余运动员以及专业运动员和退伍军人。CTE已成为一个主要的公共卫生问题。
Chronic traumatic encephalopathy (CTE) is a distinctive neurodegenerative disease that occurs as a result of repetitive head impacts. CTE can only be diagnosed by postmortem neuropathologic examination of brain tissue. CTE is a unique disorder with a pathognomonic lesion that can be reliably distinguished from other neurodegenerative diseases. CTE is associated with violent behaviors, explosivity, loss of control, depression, suicide, memory loss and cognitive changes. There is increasing evidence that CTE affects amateur athletes as well as professional athletes and military veterans. CTE has become a major public health concern.