Brain imaging of chill reactions to pleasant and unpleasant sounds
Brain imaging of chill reactions to pleasant and unpleasant sounds
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DOI：
10.1016/j.bbr.2019.112417
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发表时间：
2020-02-17
影响因子：
2.7
通讯作者：
Lotze, M.
中科院分区：
文献类型：
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作者：
Klepzig, K.;Horn, U.;Lotze, M.
“寒意”一词指的是一种短期的身体高度兴奋事件，标志着对音乐做出反应时出现的情绪高峰体验。寒冷反应会在明确限定的时间范围内出现，并且也可以通过令人不快的声音可靠地引起。然而，以前的研究主要集中在单独选择的刺激和积极的背景上，因此限制了解释的范围。因此，我们开发了标准化的寒意范式，并使用功能磁共振成像来测试 16 名健康志愿者对愉快和不愉快的情绪声音材料的神经反应，同时收集寒意强度和皮肤电导反应数据的主观报告。正如预测的那样，我们发现无论声音材料的价数如何，与寒冷相关的自主神经兴奋都会增加。除了初级和高级听觉皮层的活动外，令人愉快和不愉快的寒战都与前岛叶、丘脑和基底神经节的活动有关。相比之下，杏仁核的反应仅与令人不快的声音引起的发冷有关。因此，由愉快和不愉快的声音引起的寒意在神经网络中共享活动，这些活动可能专门涉及情绪体验的唤醒部分。
The term 'chill' refers to a short-term bodily event of high arousal, which marks an emotional peak experience when occurring in response to music. Chill responses arise in a clearly circumscribed time frame and can also be reliably elicited by unpleasant sounds. Previous research, however, mostly focused on individually selected stimuli and positive contexts, thus, limiting the scope of interpretation. Hence, we developed a standardized chill paradigm and used fMRI to test neural responses of 16 healthy volunteers to pleasant and unpleasant emotional sound material while collecting subjective reports of chill intensity and skin conductance response data. As predicted, we found chill-associated increases in autonomic arousal regardless of the valence of the sound material. Apart from activity in primary and higher auditory cortices, both pleasant and unpleasant chills were associated with anterior insula, thalamus and basal ganglia activity. In contrast, amygdala responses were observed only in association with chills elicited by unpleasant sounds. Thus, chills elicited by pleasant and unpleasant sounds share activity in a neural network that may be specifically involved in the arousal component of an emotional experience.