Evaluation and management of proteinuria and nephrotic syndrome in children: Recommendations from a pediatric nephrology panel established at the National Kidney Foundation Conference on Proteinuria, Albuminuria, Risk, Assessment, Detection, and Elimination (PARADE)
Evaluation and management of proteinuria and nephrotic syndrome in children: Recommendations from a pediatric nephrology panel established at the National Kidney Foundation Conference on Proteinuria, Albuminuria, Risk, Assessment, Detection, and Elimination (PARADE)
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DOI：
10.1542/peds.105.6.1242
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发表时间：
2000-06-01
期刊：
影响因子：
8
通讯作者：
Ingelfinger, J
中科院分区：
文献类型：
--
作者：
Hogg, RJ;Portman, RJ;Ingelfinger, J
客观的。这篇综述文章的发展源自国家肾脏基金会关于评估和治疗蛋白尿的重要性的最新进展的共识会议。这次会议发布了一系列评估成人蛋白尿的建议。由于该问题的具体儿科方面超出了国家肾脏基金会最初出版物的范围，因此成立了一个由 6 名儿童肾病专家组成的特设委员会，他们是国家肾脏基金会会议的积极参与者，旨在为初级保健医生提供有关该主题的简明、最新的参考方法。给出的建议代表了作者的共识。这些都是基于儿童对照研究的数据（如果有的话），但许多意见必然是基于儿童的非对照系列或在成人中进行的对照试验，因为尚未进行儿童对照试验来评估所描述的许多治疗方法。 结果和结论。这些建议旨在为初级保健医生在面对出现蛋白尿的幼儿或青少年时提供有用的参考，无论这种蛋白尿是轻微的、无症状的还是更严重的，导致肾病综合征。
Objective. The development of this review article evolved from a National Kidney Foundation consensus conference on recent advances in the importance of evaluating and treating proteinuria. From this conference, a series of recommendations for the evaluation of adults with proteinuria was published. Because specific pediatric aspects of the problem were outside the scope of the original National Kidney Foundation publication, an ad hoc committee of 6 pediatric nephrologists who were active participants in the National Kidney Foundation conference was established to provide primary care physicians with a concise, up-to-date reference on this subject.Methods. The recommendations that are given represent the consensus opinions of the authors. These are based on data from controlled studies in children when available, but many of the opinions are, by necessity, based on uncontrolled series in children or controlled trials performed in adults, because controlled trials in children have not been performed to evaluate many of the treatments described.Results and Conclusions. These recommendations are intended to provide primary care physicians with a useful reference when they are faced with a young child or teenager who presents with proteinuria, whether this is mild and asymptomatic or more severe, leading to nephrotic syndrome.