The effect of technology-based interventions on pain, depression, and quality of life in patients with cancer: a systematic review of randomized controlled trials.

The effect of technology-based interventions on pain, depression, and quality of life in patients with cancer: a systematic review of randomized controlled trials.
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DOI:
10.2196/jmir.4009
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发表时间:
2015-03-13
影响因子:
7.4
通讯作者:
Jethwani K
Jethwani K
中科院分区:
医学2区
文献类型:
--
作者:
Agboola SO;Ju W;Elfiky A;Kvedar JC;Jethwani K

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癌症的负担正在增加;对未来20年的预测表明,每年的癌症病例将从2012年的1 400万增加到2 200万。然而,由于新的治疗方案的可用性,21世纪的癌症患者的寿命更长,这促使人们越来越关注维持患者的健康相关生活质量。远程医疗越来越多地被用于与传统临床环境之外的患者联系,早期的工作已经显示出其在改善癌症护理的生活质量和其他临床结果方面的重要性。本研究的目的是通过对临床试验的系统回顾,系统评估支持性远程医疗干预对癌症患者疼痛、抑郁和生活质量的影响。我们在2013年7月检索了PubMed、EMBASE、Google Scholar、CINAHL和PsycINFO,并在2015年1月再次更新了文献检索,以评估远程医疗干预在癌症护理中的作用,并将疼痛、抑郁和生活质量作为主要结局。两位作者根据预先确定的选择标准,独立审查并提取了合格的随机对照试验的数据。方法学质量采用科克伦协作网偏倚风险评估工具进行评价。在从数据库和相关参考文献中检索到的4929篇文章中,共有20项RCT纳入最终综述。这些研究在干预的类型和持续时间以及结果评估方面存在很大差异。大多数研究都是基于电话的干预措施,将患者与他们的医疗保健提供者或健康教练远程联系起来。干预时间从1周到12个月不等。总体而言,大多数研究在科克伦协作网偏倚风险工具的各个领域的偏倚风险较低,但大多数研究在分配隐藏领域的信息不足。三项研究中有两项集中于疼痛控制,其中四项集中于抑郁症,只有生活质量的研究报告了显着效果。本系统性综述表明了远程保健干预在改善癌症护理结果方面的潜力。然而,需要更多高质量的大规模试验来证明其有效性的有力证据。
The burden of cancer is increasing; projections over the next 2 decades suggest that the annual cases of cancer will rise from 14 million in 2012 to 22 million. However, cancer patients in the 21st century are living longer due to the availability of novel therapeutic regimens, which has prompted a growing focus on maintaining patients’ health-related quality of life. Telehealth is increasingly being used to connect with patients outside of traditional clinical settings, and early work has shown its importance in improving quality of life and other clinical outcomes in cancer care. The aim of this study was to systematically assess the literature for the effect of supportive telehealth interventions on pain, depression, and quality of life in cancer patients via a systematic review of clinical trials. We searched PubMed, EMBASE, Google Scholar, CINAHL, and PsycINFO in July 2013 and updated the literature search again in January 2015 for prospective randomized trials evaluating the effect of telehealth interventions in cancer care with pain, depression, and quality of life as main outcomes. Two of the authors independently reviewed and extracted data from eligible randomized controlled trials, based on pre-determined selection criteria. Methodological quality of studies was assessed by the Cochrane Collaboration risk of bias tool. Of the 4929 articles retrieved from databases and relevant bibliographies, a total of 20 RCTs were included in the final review. The studies were largely heterogeneous in the type and duration of the intervention as well as in outcome assessments. A majority of the studies were telephone-based interventions that remotely connected patients with their health care provider or health coach. The intervention times ranged from 1 week to 12 months. In general, most of the studies had low risk of bias across the domains of the Cochrane Collaboration risk of bias tool, but most of the studies had insufficient information about the allocation concealment domain. Two of the three studies focused on pain control reported significant effects of the intervention; four of the nine studies focus on depression reported significant effects, while only the studies that were focused on quality of life reported significant effects. This systematic review demonstrates the potential of telehealth interventions in improving outcomes in cancer care. However, more high-quality large-sized trials are needed to demonstrate cogent evidence of its effectiveness.
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发表时间: 2012-01-01
期刊: CANCER NURSING
影响因子: 2.6
作者:
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