''Have you seen this?'' Inflammatory lesions in the lungs of rats

''Have you seen this?'' Inflammatory lesions in the lungs of rats
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DOI:
10.1177/019262339702500520
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发表时间:
1997-09-01
影响因子:
1.5
通讯作者:
Rao, GN
Rao, GN
中科院分区:
医学4区
文献类型:
--
作者:
Elwell, MR;Mahler, JF;Rao, GN

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我们邀请读者提交他们自己的诊断挑战或不寻常的发现,或对当前病变的诊断或解释发表意见和评论。案例&dquo;Tox路径论坛;请将以下信息寄至编辑部:1)物种、性别和年龄;2)试验物品的性质/类别(如有);3)简要描述和诊断;4)照片或数据。资料不应超过两页(包括照片)。提交一份硬拷贝和一张软盘(Macintosh或PC),以表明版本,以加快快速审查和出版。投稿将被审查是否清晰,是否与期刊读者相关。评论和意见可以发送到编辑部或通过电子邮件发送到knkhan@searle。孟山都。Com或dan。G.莫顿@艾伯特。com。美国国家毒理学计划/NIEHS在美国各地不同的实验室进行了数年的慢性前毒性研究,结果显示,F344雄性和雌性大鼠的肺部出现了一系列病因不明的炎症性病变。这些研究的大鼠是由位于美国东部和西部地区的两个不同的生产殖民地提供的。
* Instructions to Authors Readers are invited to submit their own diagnostic challenges or un-usual findings or to voice opinions and comments about the current lesion diagnosis or explanation. Cases for the &dquo; Tox Path Forum&dquo; should be sent to the Editorial Office with the following information: 1) spe-cies, sex, and age; 2) the nature/class of the test article (if any); 3) brief description and diagnosis; and 4) photographs or data. The information should not exceed two pages (including photographs). Submit both a hard copy and a diskette (Macintosh or PC) indicating version, to ex-pedite rapid review and publication. Submissions will be reviewed for clarity and relevance to the journal readership. Comments and opinions may be sent to the editorial office or by e-mail to knkhan@ searle. monsanto. com or dan. g. morton@ abbott. com.A spectrum of inflammatory lesions of unknown eti-ology occurred in the lungs of male and female F344 rats from a number of prechronic toxicity studies performed for the NTP/NIEHS over a period of several years at different laboratories located throughout the United States. The rats for these studies were supplied by 2 different production colonies located in the eastern and western areas of the United States.