Neurogenesis, Myelination, and Circuitry: The Case for a Distributed Therapeutic Regimen in Down Syndrome.
Neurogenesis, Myelination, and Circuitry: The Case for a Distributed Therapeutic Regimen in Down Syndrome.
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DOI:
10.1352/1944-7558-125.2.100
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发表时间:
2020-03
期刊:
影响因子:
--
通讯作者:
Haydar TF
中科院分区:
文献类型:
--
作者:
Haydar TF
One of the overriding hopes of the Down syndrome (DS) research community is to arrive at a better understanding of how trisomy 21 affects brain development and function, and that doing so will improve quality of life and independence for people with DS. In searching for the underlying causes of intellectual disability in DS, researchers and clinicians have studied how changes to genes and cells may relate to motor and cognitive function. Thus far, alterations in many areas of the central nervous system have been found, and it is now known that, beginning before birth, different changes occur in different areas over the course of life. Because of these spatial and temporal variations, multiple approaches for addressing motor and cognitive function must be considered.
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影响因子:
5.3
作者:
Chakrabarti, Lina;Galdzicki, Zygmunt;Haydar, Tarik F.
通讯作者:
Haydar, Tarik F.
影响因子:
16.2
作者:
Olmos-Serrano JL;Kang HJ;Tyler WA;Silbereis JC;Cheng F;Zhu Y;Pletikos M;Jankovic-Rapan L;Cramer NP;Galdzicki Z;Goodliffe J;Peters A;Sethares C;Delalle I;Golden JA;Haydar TF;Sestan N
通讯作者:
Sestan N
影响因子:
3.5
作者:
Contestabile, Andrea;Fila, Tatiana;Ciani, Elisabetta
通讯作者:
Ciani, Elisabetta
影响因子:
4.3
作者:
Aziz NM;Guedj F;Pennings JLA;Olmos-Serrano JL;Siegel A;Haydar TF;Bianchi DW
通讯作者:
Bianchi DW
影响因子:
64.8
作者:
Letourneau, Audrey;Santoni, Federico A.;Antonarakis, Stylianos E.
通讯作者:
Antonarakis, Stylianos E.