Predictive Value of Adenoid-Nasopharyngeal Ratio in the Diagnosis of Secretory Otitis Media
Predictive Value of Adenoid-Nasopharyngeal Ratio in the Diagnosis of Secretory Otitis Media
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腺样体与鼻咽比值对分泌性中耳炎诊断的预测价值
DOI：
10.1177/01455613221144496
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Li Shi
中科院分区：
文献类型：
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作者：
Ping Li;Tao Li;Liang Yu;Aiping Chen;Yisha Wu;Yuzhu Wan;Li Shi
目的探讨分泌性中耳炎（OME）的相关因素，分析腺样体-鼻咽（A/N）比值对OME的诊断价值。方法收集近20年来确诊为腺样体肥大（AH）患者的资料，包括性别、年龄、病程、是否合并鼻窦炎，以及检查结果，包括锥形束CT（CBCT）鼻窦成像、鼓室导抗测试、纯音测听（PTA）、血液检查、过敏原检测等。根据Liden/Jerger分型，将患者分为B型和C型，定义为鼓室导抗异常组（TAG），其余为鼓室导抗正常组（TNG）。结果316名儿童被纳入研究。TAG组的年龄和持续时间显著更年轻和更短（6.0（4.0-9.0）vs.5.0（4.0-7.0））; 12.0（4.0-24.0）vs.6.0（2.0-12.0））。与TNG相比，fx 5的过敏原检测结果TAG中蛋白质、牛奶、鳕鱼、小麦、花生和大豆的含量较高（0.09（0.04-0.25）vs.0.14（0.05-0.45）），但血液中嗜酸性粒细胞增多症较低（计数：0.21（0.13-0.35）vs. 0.18（0.12-0.27）;比率：3.10（1.90-4.70）vs. 2.50（1.65-3.80））。A/N比值与视觉障碍比值比较差异有统计学意义（Z =-3.770，P < 0.01）。结论A/N比值间接反映了本研究中鼓室导抗的异常。当A/N比值达到0.815时，患者发生OME的风险更高，因此它可能是腺样体肥大患者发生OME的预测因子。
Objectives To explore the associated factors of otitis media with effusion (OME) and analyze the diagnostic value of the adenoid-nasopharyngeal (A/N) ratio to OME. Methods Patients with adenoid hypertrophy (AH) recently in 2years were collected, including sex, age, duration, with/without rhinosinusitis, and examination results, including Cone Beam Computerized Tomography (CBCT) sinus imaging, tympanometry, pure tone audiometry (PTA), blood test, and allergen detection. According to Liden/Jerger’s classification, the patients were divided into two groups: Type B and type C, which were defined as the tympanometry abnormal group (TAG), and the rest were classified as the tympanometry normal group (TNG). Results A total of 316 children were included in this study. Age and duration were significantly younger and shorter in TAG (6.0(4.0-9.0) vs.5.0(4.0-7.0)); 12.0(4.0-24.0) vs.6.0(2.0-12.0)). Compared to TNG, the allergen test results of fx5 (protein, milk, cod, wheat, peanut, and soybean) in TAG were higher (0.09(0.04-0.25) vs.0.14(0.05-0.45)), but eosinophilia in blood was lower (count: 0.21(0.13-0.35) vs. 0.18(0.12-0.27); ratio: 3.10 (1.90-4.70) vs. 2.50 (1.65-3.80)). A/N ratio and Visual obstruction ratio had a statistical difference (Z = −3.770, P Conclusions A/N ratio indirectly reflected the abnormality of tympanometry in this study. When A/N ratio reaches 0.815, patients are at a higher risk of having OME so it could be a predictor of OME in patients with adenoid hypertrophy.