Pain and opioid use in chronic liver disease: optimal treatment must address the mental health care needs of the patient.
Pain and opioid use in chronic liver disease: optimal treatment must address the mental health care needs of the patient.
复制标题
慢性肝病中的疼痛和阿片类药物的使用：最佳治疗必须满足患者的心理保健需求。
DOI：
10.1007/s10620-013-2809-4
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发表时间：
2013
影响因子：
3.1
通讯作者：
Hauser,Peter
中科院分区：
文献类型：
--
作者：
Loftis,JenniferM;Hauser,Peter
疼痛是常见的，在慢性肝病患者中治疗可能具有挑战性。由于对肝脏的影响，非甾体类阿片类药物可能未得到充分利用，而阿片类药物可能由于并发物质使用障碍诊断和相对缺乏疗效而在该患者人群中存在独特的挑战。更好地了解与疼痛相关的因素可能会揭示重要的见解，有望改善这一人群的疼痛管理。根据迄今为止发表的研究，常规筛查和治疗共病精神疾病，特别是抑郁症，将改善慢性肝病患者的疼痛缓解。
Pain is common and can be challenging to treat among patients with chronic liver disease. Non-steroidal antiinflammatory medications may be underutilized due to their effects on the liver, and opiates may present unique challenges in this population of patients due to concurrent substance use disorder diagnoses and relative lack of efficacy. A better understanding of the factors involved and associated with pain may reveal important insights that promise to improve pain management in this population. Based on studies published to date, routinely screening for and treating co-morbid psychiatric disorders, and, in particular, depressive disorders, would improve the alleviation of pain in people with chronic liver disease.