Carbon dioxide insufflation improves the intubation depth and total enteroscopy rate in single-balloon enteroscopy: a randomised, controlled, double-blind trial
Carbon dioxide insufflation improves the intubation depth and total enteroscopy rate in single-balloon enteroscopy: a randomised, controlled, double-blind trial
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DOI：
10.1136/gutjnl-2013-306069
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发表时间：
2014-10-01
期刊：
影响因子：
24.5
通讯作者：
Ge, Zhi-Zheng
中科院分区：
文献类型：
--
作者：
Li, Xuan;Zhao, Yun-Jia;Ge, Zhi-Zheng
目的单气囊小肠镜（single-balloonenteroscopy，SBE）充气法的全肠镜检查率不高，二氧化碳（CO2）充气法能否提高SBE的全肠镜检查率尚不清楚。这项随机对照试验的目的是确定是否CO2吹入有利于插管深度和总肠镜率SBE.Design一个符合条件的214例患者提到SBE随机接受空气或CO2吹入，并包括在意向测试（ITT）分析。此外，199例完成肠镜检查的患者被纳入符合方案（PP）分析。结果在ITT分析中，CO2组显示出插管的优越性（经口途径：323.8 +/- 64.2 vs 238.3 +/- 68.6 cm;经肛门途径：261.6 ± 74.2 vs 174.7 ± 62.1 cm，均为p
Objective The total enteroscopy rate of single-balloon enteroscopy (SBE) using air insufflation is not satisfactory, and whether carbon dioxide (CO2) insufflation increases the total enteroscopy rate of SBE is unknown. This randomised controlled trial aimed to determine whether CO2 insufflation facilitates the intubation depth and total enteroscopy rate of SBE.Design A total of 214 eligible patients referred for SBE were randomised to receive either air or CO2 insufflation, and included in the intention-to-test (ITT) analysis. In addition, 199 patients in whom enteroscopy was completed were included in the per-protocol (PP) analysis. Both the patients and endoscopists were blinded, and the intubation depth and total enteroscopy rate were defined as the primary outcomes.Results The CO2 group showed a superiority of intubation in the ITT analysis (oral route: 323.8 +/- 64.2 vs 238.3 +/- 68.6 cm; anal route: 261.6 +/- 74.2 vs 174.7 +/- 62.1 cm, both p