Focal impulse and rotor modulation ablation of sustaining rotors abruptly terminates persistent atrial fibrillation to sinus rhythm with elimination on follow-up: A video case study
Focal impulse and rotor modulation ablation of sustaining rotors abruptly terminates persistent atrial fibrillation to sinus rhythm with elimination on follow-up: A video case study
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DOI：
10.1016/j.hrthm.2012.03.055
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发表时间：
2012-09-01
期刊：
影响因子：
5.5
通讯作者：
Krummen, David E.
中科院分区：
文献类型：
--
作者：
Narayan, Sanjiv M.;Patel, Jigar;Krummen, David E.
讨论这是基于维持转子的检测和靶向消融的临床AF治疗的首次演示。在这位63岁的男性患者中，尽管之前进行了迷宫消融术，然后进行了腔内消融术，但持续性房颤至少10个月，新型计算标测显示左右心房持续存在转子。每个转子的靶向（FIRM）消融突然终止了AF至窦性心律。这在任何肺静脉标测或消融之前迅速实现。患者结论
DiscussionThis is the first demonstration of clinical AF therapy based on the detection and targeted ablation of sustaining rotors. In this 63-year-old gentleman with persistent AF for at least 10 months despite prior Maze and then endocardial ablation procedures, novel computational mapping revealed sustained rotors in the right and left atria. Targeted (FIRM) ablation at each rotor abruptly terminated AF to sinus rhythm. This was achieved rapidly prior to any PV mapping or ablation. The patient isConclusions