DISTRIBUTION OF MODIFIED NUCLEOSIDE Q AND ITS DERIVATIVES IN ANIMAL AND PLANT TRANSFER-RNAS
DISTRIBUTION OF MODIFIED NUCLEOSIDE Q AND ITS DERIVATIVES IN ANIMAL AND PLANT TRANSFER-RNAS
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DOI：
10.1093/nar/2.10.1931
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发表时间：
1975-01-01
影响因子：
14.9
通讯作者：
NISHIMURA, S
中科院分区：
文献类型：
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作者：
KASAI, H;KUCHINO, Y;NISHIMURA, S
修饰的核苷7-（4，5-顺式-二羟基-1-环戊烯-3-基-氨甲基）-7-脱氮鸟苷（简称Q）及其衍生物Q ~* 存在于多种生物的tRNA中，包括哺乳动物组织、海星、舌形动物、盲鳗和小麦胚芽。coliQ通过质谱法和薄层色谱法。因此，最初弗罗姆. colitRNA广泛分布于各种生物体中。Q* 的质谱分析表明其具有与Q不同的侧链。
The modified nucleoside, 7-(4,5-cis-dihydroxy-l-cyclopenten-3-yl-aminomethyl)-7-deazaguanosine, designated as Q, and its derivative, Q*, were found in tRNA's from various organisms, including several mammalian tissues, other animals such as starfish, lingula and hagfish, and wheat germ.Q isolated from rat liver tRNA was found to be identical withE. coliQ by mass spectrometry and thin-layer chromatography. Thus the rare modified nucleoside Q originally isolated fromE. colitRNA, is widely distributed in various organisms. Analysis of the mass spectrum of Q*suggested that it has a different side chain from Q.