Edge-based growth control in Arabidopsis involves two cell wall-associated Receptor-Like Proteins
Edge-based growth control in Arabidopsis involves two cell wall-associated Receptor-Like Proteins
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DOI：
10.1101/2022.06.10.495700
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发表时间：
2022-06
期刊：
影响因子：
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通讯作者：
Liam Elliott;M. Kalde;Ann-Kathrin Schuerholz;Sebastian Wolf;I. Moore;Charlotte Kirchhelle
中科院分区：
文献类型：
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作者：
Liam Elliott;M. Kalde;Ann-Kathrin Schuerholz;Sebastian Wolf;I. Moore;Charlotte Kirchhelle
多细胞器官的形态发生需要细胞生长的协调。在植物中，3D生长是由非定向膨胀压力驱动的，而生长方向是由2D细胞面的细胞壁机械特性控制的。它们共享的细胞壁也将细胞固定在它们的位置上，因此植物必须整合由于在固定的组织拓扑中生长而产生的组织规模的机械应力。这意味着需要监测细胞壁的机械和生化状态，并相应地适应生长。在这里，我们建议植物细胞利用它们的一维细胞边缘来监测细胞壁的状态。我们描述了两个受体样蛋白，RLP4和RLP4-L1，它们在通过靶向分泌运输途径建立的细胞边缘占据一个独特的极性区域。我们发现，在细胞边缘，RLP4通过其胞外结构域与细胞壁结合，并有助于拟南芥的定向生长控制。
Morphogenesis of multicellular organs requires coordination of cellular growth. In plants, 3D growth is driven by undirected turgor pressure, whereas growth directionality is controlled by cell wall mechanical properties at 2D cell faces. Their shared cell wall also fixes cells in their position, and plants thus have to integrate tissue-scale mechanical stresses arising due to growth in a fixed tissue topology. This implies a need to monitor cell wall mechanical and biochemical status and to adapt growth accordingly. Here, we propose that plant cells use their 1D cell edges to monitor cell wall status. We describe two Receptor-Like Proteins, RLP4 and RLP4-L1, which occupy a unique polarity domain at cell edges established through a targeted secretory transport pathway. We show that at cell edges, RLP4s associate with the cell wall via their extracellular domain, and contribute to directional growth control in Arabidopsis.