Screening for depression and anxiety in patients with storage or voiding dysfunction: A retrospective cohort study predicting outcome of sacral neuromodulation

Screening for depression and anxiety in patients with storage or voiding dysfunction: A retrospective cohort study predicting outcome of sacral neuromodulation
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DOI:
10.1002/nau.22871
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发表时间:
2016-11-01
影响因子:
2
通讯作者:
van Koeveringe, Gommert
van Koeveringe, Gommert
中科院分区:
医学3区
文献类型:
--
作者:
Drossaerts, Jamie;Vrijens, Desiree;van Koeveringe, Gommert

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目的有报道称,对有情感症状的患者进行躯体化治疗有较高的失败风险。目的是调查情感症状是否可以预测骶神经调节(SNM)治疗下尿路症状(LUTS)的结果。方法纳入2006年至2013年期间接受SNM评估并在治疗前填写医院焦虑和抑郁评分(HADS)的所有患者。卡方分析和双变量Logistic回归被用来评估协会和预测value.Results86例患者,65名女性和21名男性。大多数患者(66例)患有膀胱过度活动综合征(OAB)。其余20例为非梗阻性尿潴留(NOR)。39名OAB患者和17名NOR患者在治疗前的总HADS评分正常。OAB组中HADS-D(P=0.047)和HADS-A(P=0.015)评分异常的患者显著多于NOR组。SNM的成功不能通过HADS评分P=0.464来预测(1年后P=0.446)。随后的分析显示,异常的HADS评分是不相关的SNM不良事件的发生。ConclusionsThe目前的研究并没有揭示一个异常的HADS评分和失败的SNM测试期间的OAB和NOR患者的混合组之间的显着关系。然而,OAB和NOR患者之间的情感症状的差异。已知心理因素在LUTS的严重程度中起作用,但它们可能无法预测SNM结果。Neurorol。Urodynam。35:1011-1016,2016. (c)2015 Wiley Periodicals,Inc.
AimsIt has been reported that somatic treatment in patients with affective symptoms has a higher risk of failure. The aim was to investigate whether affective symptoms could predict the outcome of sacral neuromodulation (SNM) for lower urinary tract symptoms (LUTS).MethodsAll patients that underwent a SNM evaluation between 2006 and 2013 and filled out a Hospital Anxiety and Depression Score (HADS) before treatment, were included. Chi-square analysis and bivariate logistic regression were used to assess associations and predictive value.ResultsEighty-six patients were included, 65 females and 21 males. Most patients, 66, had overactive bladder syndrome (OAB). The remaining 20 patients suffered from non-obstructive urinary retention (NOR). Thirty-nine OAB patients and 17 NOR patients, had a normal total HADS score before treatment. Significantly more patients showed abnormal HADS-D (P=0.047) and HADS-A (P=0.015) scores in the OAB group compared to the NOR group. Success of SNM could not be predicted by the HADS score P=0.464 (after 1 year P=0.446). Subsequent analysis revealed that an abnormal HADS score was not related to the occurrence of SNM adverse events.ConclusionsThe present study did not reveal a significant relationship between an abnormal HADS score and failure of the SNM test period in a mixed group of OAB and NOR patients. However, differences between OAB and NOR patients concerning affective symptoms were present. It is known that psychological factors play a role in the severity of LUTS, but they may not predict SNM outcome. Neurourol. Urodynam. 35:1011-1016, 2016. (c) 2015 Wiley Periodicals, Inc.