A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells
A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells
复制标题
用于检测活细胞中谷胱甘肽的近红外比色荧光化学剂量计
DOI：
10.1039/c3cc48128j
复制
发表时间：
2014-01-01
影响因子：
4.9
通讯作者：
James, Tony D.
中科院分区：
文献类型：
--
作者：
Li, Meng;Wu, Xumeng;James, Tony D.
基于二氰基亚甲基-4H-吡喃发色团，设计了一种新型的近红外（NIR）比色荧光分子探针，用于活细胞中谷胱甘肽的选择性检测。通过与GSH的相互作用切割2，4-二硝基苯磺酰基（DNBS）单元触发荧光关闭-打开开关。
A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF-ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.