HIGH PREVALENCE OF INVASIVE HAEMOPHILUS INFLUENZAE DISEASE IN CENTRAL AUSTRALIA, 1986

HIGH PREVALENCE OF INVASIVE HAEMOPHILUS INFLUENZAE DISEASE IN CENTRAL AUSTRALIA, 1986
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1986 年澳大利亚中部侵袭性流感嗜血杆菌疾病的高流行

DOI:
10.1016/s0140-6736(86)90451-4
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发表时间:
1986
期刊:
The Lancet
影响因子:
--
通讯作者:
F. Morey
F. Morey
中科院分区:
--
文献类型:
--
作者:
D. Hansman;J. Hanna;F. Morey

文献摘要

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在12个月的时间里(1985年6月至1986年5月),澳大利亚中部约11000名原住民中发生了17例全身性流感嗜血杆菌感染(脑膜炎7例,菌血症6例,肺炎4例),其中1540例是5岁以下的儿童。所有这些感染均发生在 2 岁以下的儿童中。这些数字相当于1100/100 000名5岁以下儿童的发病率,这是非常高的。同期7例H.澳大利亚中部的非原住民儿童中也发现了流感侵袭性疾病(5岁以下儿童的发病率为350/100 000),发病率也很高。阿德莱德儿童医院的数据显示,南澳州南部(约占全州人口的95%)5岁以下儿童的发病率约为30/100 000。原住民儿童的病例发生在人口稀少的大片地区。因此,高发病率不太可能是局部流行病的结果。因此,像澳大利亚中部和阿拉斯加这样气候不同的地区,幽门螺杆菌的发病率很高。流感疾病,可能与拥挤和其他不利的社会经济因素有关。newline〜M.P.E.松弛
During a 12-month period (June 1985-May 1986) 17 cases of systemicHaemophilus influenzaeinfection (meningitis 7, bacteraemia 6, pneumonia 4) occurred in an aboriginal population of about 11 000 in central Australia, of whom 1540 were children <5 years of age. All these infections were in children <2 years of age. These figures are equivalent to an attack rate of 1100/100 000 children <5 years of age, which is exceptionally high. During the same period 7 cases ofH. influenzaeinvasive disease were detected in non-aboriginal children in central Australia (attack rate 350/100 000 children <5 years) which is also high. Data from the Adelaide Children's Hospital show that the rate in southern South Australia (which contains about 95% of the state's population) is about 30/100 000 children <5 years of age.The cases in aboriginal children occurred over a large and sparsely populated area. It is unlikely therefore that the high incidence rate is the result of a localized epidemic. Thus regions with climates as different as those of central Australia and Alaska share a high incidence ofH. influenzaedisease, which may be related to crowding and other adverse socioeconomic factors.newline˜M.P.E. Slack