Antimicrobial resistance in major pathogens of hospital-acquired pneumonia in Asian countries
Antimicrobial resistance in major pathogens of hospital-acquired pneumonia in Asian countries
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DOI：
10.1016/j.ajic.2007.10.020
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发表时间：
2008-05-01
影响因子：
4.9
通讯作者：
Lagamayo, Evelina N.
中科院分区：
文献类型：
--
作者：
Lagamayo, Evelina N.
抗生素耐药性是一个世界性的问题。对于医院获得性肺炎或呼吸机相关性肺炎患者，耐药病原体对成功的治疗结果和具有成本效益的医疗保健服务构成了重大挑战。在发展中国家，与西方国家相比，抗生素耐药性可能相对更为普遍。常见的耐药病原体包括耐甲氧西林金黄色葡萄球菌、多重耐药铜绿假单胞菌、多重耐药不动杆菌属以及产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌。这些菌株的出现为亚洲HAP工作组目前一致的治疗建议的发展提供了主要动力。以下综述提供了10个亚洲国家耐药病原体发生率和流行率的汇总数据。
Antimicrobial resistance is a worldwide problem. For patients with hospital-acquired or ventilator-associated pneumonia, resistant pathogens pose a significant challenge to successful treatment outcomes and to the cost-effective delivery of health care. In the developing world, antibiotic resistance may be relatively more prevalent compared with Western countries. Common resistant pathogens include methicillin-resistant Staphylococcus aureus, multidrug resistant Pseudomonas aeruginosa, multidrug resistant Acinetobacter species, and extended-spectrum beta-lactamase-producing strains of Escherichia coli and Klebsiella pneumoniae. The emergence of these strains has provided a major impetus toward development of the present consensus treatment recommendations of the Asian HAP Working Group. The following review provides summary data regarding the incidence and prevalence of antibiotic-resistant pathogens in 10 Asian countries.