Fungi: outstanding source of novel chemical scaffolds

Fungi: outstanding source of novel chemical scaffolds
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真菌:新型化学支架的重要来源

DOI:
10.1080/10286020.2018.1488833
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发表时间:
2020-02-01
影响因子:
1.7
通讯作者:
Liu, Yun-Bao
Liu, Yun-Bao
中科院分区:
医学4区
文献类型:
--
作者:
Liu, Zhen;Zhao, Jing-Yi;Liu, Yun-Bao

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摘要近年来,人们对真菌次生代谢产物进行了大量卓有成效的研究。本文综述了2013年至2017年发表的79篇文章中报道的167种具有新骨架及其生物活性的分子。我们的统计数据表明,内生真菌和海洋来源的真菌是新的生物活性次生代谢产物的主要来源。
Abstract A large number of remarkable studies on the secondary metabolites of fungi have been conducted in recent years. This review gives an overview of one hundred and sixty-seven molecules with novel skeletons and their bioactivities that have been reported in seventy-nine articles published from 2013 to 2017. Our statistical data showed that endophytic fungi and marine-derived fungi are the major sources of novel bioactive secondary metabolites.