Isolates of the emerging pathogen Candida auris present in the UK have several geographic origins

Isolates of the emerging pathogen Candida auris present in the UK have several geographic origins
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DOI:
10.1093/mmy/myw147
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发表时间:
2017-07-01
期刊:
影响因子:
2.9
通讯作者:
Johnson, Elizabeth M.
Johnson, Elizabeth M.
中科院分区:
医学3区
文献类型:
--
作者:
Borman, Andrew M.;Szekely, Adrien;Johnson, Elizabeth M.

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耳念珠菌最近已成为严重的医院健康风险,在全球许多医院广泛爆发,并且存在地理区域特异性离散克隆谱系。在这里,我们比较了来自英国14个不同医院中心的24株金黄色念珠菌的rDNA序列与公共序列数据库中来自不同国际来源的菌株的rDNA序列。在这里,我们表明,英国分离的金黄色葡萄球菌属于三个支持良好的分支,与先前分别在印度、马来西亚和科威特、日本和韩国和南非报道的谱系相对应。
Candida auris has recently emerged as a serious nosocomial health risk, with widespread outbreaks in numerous hospitals worldwide and the existence of geographic region-specific discrete clonal lineages. Here we have compared the rDNA sequences of 24 isolates of Candida auris from 14 different hospital centers in the United Kingdom with those of strains from different international origins present in the public sequence databases. Here we show that UK isolates of C. auris fall into three well-supported clades corresponding to lineages that have previously been reported from India, Malaysia and Kuwait, Japan and Korea, and South Africa, respectively.