Renal injury in neonates: use of "omics" for developing precision medicine in neonatology.

Renal injury in neonates: use of "omics" for developing precision medicine in neonatology.
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新生儿肾损伤:利用“组学”开发新生儿精准医学。

DOI:
10.1038/pr.2016.206
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发表时间:
2017
期刊:
影响因子:
3.6
通讯作者:
Hanna,MinaH
Hanna,MinaH
中科院分区:
医学3区
文献类型:
--
作者:
Joshi,MandarS;Montgomery,KelseyA;Giannone,PeterJ;Bauer,JohnA;Hanna,MinaH

文献摘要

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早产与发病率和死亡率的风险增加以及医疗保健费用的增加沿着。医学的进步提高了早产儿的存活率,但主要疾病的总体发病率变化很小。肾脏发育异常是早产的一个重要后果。新生儿期的急性肾损伤(阿基)是多因素的,可能会增加慢性肾脏疾病的终生风险。
Preterm birth is associated with increased risks of morbidity and mortality along with increased healthcare costs. Advances in medicine have enhanced survival for preterm infants but the overall incidence of major morbidities has changed very little. Abnormal renal development is an important consequence of premature birth. Acute kidney injury (AKI) in the neonatal period is multifactorial and may increase lifetime risk of chronic kidney disease.