Neonatal gonococcal infection. I. Orogastric contamination with Neisseria gonorrhoea.
Neonatal gonococcal infection. I. Orogastric contamination with Neisseria gonorrhoea.
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新生儿淋球菌感染。
DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
K. Holmes
中科院分区：
文献类型：
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作者：
H. Handsfield;W. A. Hodson;K. Holmes
从西雅图的14名新生儿的口胃吸出物（OGA）中分离出淋病奈瑟菌，其中包括9名在华盛顿大学医院出生的新生儿，为期4年。早产，胎膜长时间破裂，相关的产妇围产期发热，绒毛膜炎，OGA白细胞增多的组织学证据，和败血症的临床诊断更常见的婴儿中OGA含有淋球菌比153婴儿OGA显示没有致病菌。围产期子宫颈内、子宫内膜或胎盘标本中含有淋病奈瑟菌的母亲早产和胎膜破裂的频率增加。淋球菌感染可能对妊娠过程产生不利影响，导致产妇和婴儿发病。淋病奈瑟菌口腔-胃污染可能是目前新生儿淋病奈瑟菌定植最常见的形式。
Neisseria gonorrhoeae was isolated from the orogastric aspirates (OGA) of 14 neonates in Seattle, including nine born at the University of Washington Hospital over a four-year period. Prematurity, prolonged rupture of the fetal membranes, associated maternal peripartum fever, histologic evidence of chorioamnionitis, OGA leukocytosis, and a clinical diagnosis of sepsis were more frequent among the infants whose OGA contained gonococci than among 153 infants whose OGA showed no pathogenic bacteria. Mothers whose peripartum endocervical, endometrial, or placental specimens contained N gonorrhoeae had an increased frequency of premature delivery and prolonged rupture of membranes. Gonococcal infection may have an adverse effect on the course of pregnancy, with resultant maternal and infant morbidity. Gonococcal amniotic-orogastric contamination is probably the most common form of neonatal colonization by N gonorrhoeae at the present time.