Cassiarins A and B, novel antiplasmodial alkaloids from Cassia siamea

Cassiarins A and B, novel antiplasmodial alkaloids from Cassia siamea
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DOI:
10.1021/ol701623n
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发表时间:
2007-08-30
期刊:
影响因子:
5.2
通讯作者:
Zaini, Noor Cholies
Zaini, Noor Cholies
中科院分区:
化学1区
文献类型:
--
作者:
Morita, Hiroshi;Oshimi, Shiori;Zaini, Noor Cholies

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从决明子叶中分离得到两个新的三环生物碱,分别为决明子A(1)和B(2),其结构经波谱数据确证。决明子甲素(1)具有较强的抗疟原虫活性。
Two novel alkaloids with an unprecedented tricyclic skeleton, cassiarins A (1) and B (2), have been isolated from the leaves of Cassia siamea, and the structures were elucidated on the basis of spectroscopic data. Cassiarin A (1) showed a potent antiplasmodial activity.