Visible-Light-Induced 3-Component Synthesis of Sulfonylated Oxindoles by Fixation of Sulfur Dioxide
Visible-Light-Induced 3-Component Synthesis of Sulfonylated Oxindoles by Fixation of Sulfur Dioxide
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DOI：
10.1002/ejoc.201801128
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发表时间：
2018-11-08
影响因子：
2.8
通讯作者：
Manolikakes, Georg
中科院分区：
文献类型：
--
作者：
Liu, Nai-Wei;Chen, Zhengkai;Manolikakes, Georg
报道了以N-芳基丙烯酰胺、二芳碘盐和二氧化硫为原料，在可见光诱导下合成磺化氧吲哚的新方法。该反应提供了一种简单的途径，在温和的条件下，在室温下以中等到极好的产率合成了多种3-[(芳基磺酰基)甲基]吲哚-2-酮。这种转化是在没有任何外部光敏剂的情况下进行的，能够实现高效的、完全由可见光驱动的二氧化硫固定。
A novel, visible-light-induced 3-component synthesis of sulfonylated oxindoles from N-arylacrylamides, diaryliodonium salts and sulfur dioxide is described. The reaction provides simple access to a wide variety of 3-[(arylsulfonyl)methyl]indolin-2-ones in moderate to excellent yields under mild conditions at room temperature. The transformation proceeds in the absence of any external photosensitizer and enables an efficient, solely visible-light-driven fixation of sulfur dioxide.