Investigation of multifocal choroiditis with panuveitis by three‐dimensional high‐penetration optical coherence tomography
Investigation of multifocal choroiditis with panuveitis by three‐dimensional high‐penetration optical coherence tomography
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DOI：
10.1002/jbio.200910017
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发表时间：
2009-07
影响因子：
2.8
通讯作者：
Y. Yasuno;F. Okamoto;K. Kawana;T. Yatagai;T. Oshika
中科院分区：
文献类型：
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作者：
Y. Yasuno;F. Okamoto;K. Kawana;T. Yatagai;T. Oshika
通过三维 (3-D) 高穿透光学相干断层扫描对一例多灶性脉络膜炎伴全葡萄膜炎 (MFCPU) 进行了研究。 HP-OCT基于扫频OCT技术，使用中心波长为1060 nm的探测光束，具有10.4μmin组织的深度分辨率。本研究涉及 MFCPU 患者的两只眼睛。还通过彩色眼底照片、荧光素血管造影（FA）和吲哚青绿血管造影（ICGA）检查眼睛。对这四种模式的研究结果进行了比较讨论。 OCT 扫描揭示了病变部位的以下特征。视网膜变薄、视网膜层破坏以及感光器内节和外节的连接处消失（IS/OS）。由于该 OCT 系统的高穿透性，还观察到病变的以下特征：脉络膜局部变薄、脉络膜血管闭塞以及可能代表脉络膜色素沉着过度的局部高反射率。 （© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA，魏因海姆）
A single case of multifocal choroiditis with panuveitis (MFCPU) was investigated by a three‐dimensional (3‐D) high‐penetration optical coherence tomography. The HP‐OCT is based on a swept‐source OCT technology, uses a probe beam with a center wavelength of 1060 nm, and possesses a depth resolution of 10.4 μ min tissue. Two eyes of an MFCPU patient were involved in this study. The eyes were also examined by color fundus photograph, fluorescein angiography (FA), and indocyanine green angiography (ICGA). Findings in these four modalities are comparatively discussed. The OCT scans revealed the following characteristic properties of the lesion sites. Thinning of the retina, destructuring of the retinal layers, and disappearance of the junction of the inner and outer segments of the photoreceptor (IS/OS). Due to the high penetration of this OCT system, the following characteristic properties of the lesions were also observed: localized thinning of the choroid, occlusion of the choroidal vessels, and localized hyper‐reflectivity that may represent hyper‐pigmentation of the choroid. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)