Sesquiterpenes from the essential oil of Laurencia dendroidea (Ceramiales, Rhodophyta): isolation, biological activities and distribution among seaweeds

Sesquiterpenes from the essential oil of Laurencia dendroidea (Ceramiales, Rhodophyta): isolation, biological activities and distribution among seaweeds
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DOI:
10.1590/s0102-695x2011005000059
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发表时间:
2011-04-01
期刊:
Revista Brasileira de Farmacognosia
影响因子:
--
通讯作者:
Pinto, Ernani
Pinto, Ernani
中科院分区:
其他
文献类型:
--
作者:
Gressler, Vanessa;Stein, Érika M.;Pinto, Ernani

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2个已知的倍半萜(1R*,2S*,3R*,5S*,8S*,9R*)-2,3,5,9-tetramethyltricyclo[6.3.0.0(1,5)]undecan-2-ol和(1S*,2S*,3S*,5S*,8S*,9S*)-2,3,5,9-tetramethyltricyclo-[6.3.0.0(1,5)]undecan-2-ol)均为首次从巴西海藻精油中分离得到。这些化合物对8株细菌和酵母菌白色念珠菌没有活性,但显示出一定的抗氧化活性。在其他海藻中也发现了这两种化合物,表明它们不是Laurencia属的唯一分类标记。
Two known sesquiterpenes (1R*, 2S*, 3R*, 5S*, 8S*, 9R*)-2,3,5,9-tetramethyltricyclo[6.3.0.0(1,5)]undecan-2-ol and (1S*, 2S*, 3S*, 5S*, 8S*, 9S*)-2,3,5,9-tetramethyltricyclo-[6.3.0.0(1,5)]undecan-2-ol were isolated for the first time from the essential oil of the red seaweed Laurencia dendroidea collected in the Brazilian coast. These compounds were not active against eight bacteria strains and the yeast Candida albicans, but showed some antioxidant activity. Both compounds were also found in other seaweed species showing that they are not exclusive taxonomic markers to the genus Laurencia.