Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging
Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging
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DOI：
10.1088/0031-9155/61/12/4583
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发表时间：
2016-05
影响因子：
3.5
通讯作者：
M. Ahlborg;C. Kaethner;Tobias Knopp;Tobias Knopp;P. Szwargulski;P. Szwargulski;T. Buzug
中科院分区：
文献类型：
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作者：
M. Ahlborg;C. Kaethner;Tobias Knopp;Tobias Knopp;P. Szwargulski;P. Szwargulski;T. Buzug
成像技术磁性粒子成像允许通过经由磁场的材料的再磁化来检测磁性材料，特别是超顺磁性纳米颗粒。该应用旨在医学成像，其中颗粒作为示踪剂直接应用于血流中。诸如外周神经刺激的医疗安全考虑限制了磁场的最大幅度，进而限制了视野大小。为了处理这种约束，引入了贴片的概念，其允许将视场移位到不同位置以扩大成像区域。如果这是静态完成的，则可以使用面片的重叠来减少在相邻边缘处发生的截断伪影。在这方面的贡献，区分两种不同类型的补丁重叠，即轨迹和系统矩阵重叠。此外，不同的概念，以联合收割机合并所产生的冗余信息进行了研究，相对于截断伪影的减少。在仿真研究中对该方法进行了详细分析，并在实验数据上进行了验证。
The imaging technology magnetic particle imaging allows the detection of magnetic material, in particular superparamagnetic nanoparticles, by remagnetization of the material via magnetic fields. The application is aimed at medical imaging where the particles are applied as tracer directly into the blood stream. Medical safety considerations such as peripheral nerve stimulation limit the maximal amplitude of the magnetic fields and in turn the field of view size. To handle this constraint the concept of patches was introduced, which allows a shift of a field of view to different positions in order to enlarge the imaging area. If this is done statically an overlap of patches can be used to reduce truncation artifacts occurring at the adjacent edges. In this contribution, a differentiation of two different kinds of patch overlaps, i.e. a trajectory and a system matrix overlap, is made. Further, different concepts to combine the resulting redundant information are investigated with respect to the reduction of truncation artifacts. The methods are analyzed in detail in a simulation study and validated on experimental data.